
Central giant cell granuloma in the mandibula: clinical, radiological and histopathological study in 2 clinical cases
Author(s) -
Ţîbîrnă Gheorghe,
Silvia Răilean,
Egor Porosencov,
Tatiana Porosencova,
Roman Lupan
Publication year - 2021
Publication title -
buletinul academiei de ştiinţe a moldovei: ştiinţe medicale
Language(s) - English
Resource type - Journals
ISSN - 1857-0011
DOI - 10.52692/1857-0011.2021.2-70.18
Subject(s) - etiology , lesion , central giant cell granuloma , medicine , incidence (geometry) , granuloma , pathology , population , radiological weapon , surgery , physics , environmental health , optics
Central giant cell granuloma (CGCG) is a benign and proliferative lesion of the jaw, with an unknown etiology. It is widely considered to be a neoplastic lesion. The current etiology of GCGC is still unclear, although local inflammation, bleeding, and trauma have been suggested. The biological behavior of CGCG of the jaw varies from resting to aggressive with destructive expansion. The incidence in the general population is very low, and patients are generally under 30 years of age females. In this study, we report two cases of GCGC in 8-year-old and 13 year old girls treated surgically.