Open AccessAntibacterial therapy of community-acquired pneumonia
Author(s) -
Nicolae Bacinschi,
Cristina Plesca,
Anastasia Caracaş,
Eugenia Vasilache,
Dumitru Stirba,
Ina Guţu
Publication year - 2021
Publication title -
buletinul academiei de ştiinţe a moldovei: ştiinţe medicale
Language(s) - English
Resource type - Journals
ISSN - 1857-0011
DOI - 10.52692/1857-0011.2021.1-69.24
Subject(s) - cefuroxime , ceftriaxone , ceftazidime , medicine , cefazolin , pneumonia , cephalosporin , antibiotics , community acquired pneumonia , antimicrobial , intensive care medicine , cefoxitin , microbiology and biotechnology , biology , bacteria , genetics , pseudomonas aeruginosa , staphylococcus aureus
Cephalosporins, and primarily ceftriaxone, were the main group of antibiotics used as monotherapy in case of community-acquired pneumonia of inpatient treatment. Macrolides and fluoroquinolones have been used predominantly in combination with cephalosporins (ceftriaxone, ceftazidime, cefuroxime, cefazolin) in patients with comorbidities. The selection of empirical antibacterial preparations was based on subjective, objective, laboratory and radiological data, as well as by analyzing epidemiological data and antibacterial resistance in hospital. The optimal strategy in the selection of antibiotics or their combinations is determined by covering spectrum of possible microbial agents, obtaining a synergistic antimicrobial effect and avoiding potential adverse reactions.