Open AccessElectrophysiological Recordings from Embryonic Mouse Motoneurons Cultured on Electrospun Poly-Lactic Acid (PLA) and Polypyrrole-Coated PLA Scaffolds
Author(s) -
Esmeralda Zuñiga,
Odin Ramírez,
Carlos Andrés López Martinez
Publication year - 2022
Publication title -
iranian biomedical journal.
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.519
H-Index - 31
eISSN - 2008-823X
pISSN - 1028-852X
DOI - 10.52547/ibj.26.3.183
Subject(s) - electrophysiology , biophysics , chemistry , microbiology and biotechnology , adhesion , self healing hydrogels , lactic acid , spinal cord , neuroscience , polymer chemistry , biology , genetics , organic chemistry , bacteria
Biomaterials used as cell growth stimulants should be able to provide adequate cell adhesion with no alteration in cell function. In this work, we developed a three-dimensional model of mouse spinal cord motoneurons on scaffolds composed of electrospun poly-lactic acid (PLA) fibers and plasma-polymerized polypyrrole (PPy)-coated PLA fibers.