Open AccessMechanism-based pharmacokinetic/pharmacodynamic modeling of the effects of sitagliptin on DPP-4 activity, insulin and glucose in diabetic rats
Author(s) -
Ye Yao,
Xiang-Fei Jiu,
Siyuan Wang,
Wei Lü,
Tianyan Zhou
Publication year - 2018
Publication title -
journal of chinese pharmaceutical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.138
H-Index - 12
ISSN - 1003-1057
DOI - 10.5246/jcps.2018.06.038
Subject(s) - sitagliptin , pharmacodynamics , pharmacology , pharmacokinetics , diabetes mellitus , insulin , mechanism (biology) , medicine , endocrinology , type 2 diabetes , philosophy , epistemology