Diagnostics and treatment of high productive cows patients with ketosis in the conditions of the natural-technogenic province of the Middle Urals

The article presents the results of a study on the diagnosis and effectiveness of therapy methods for cows with ketosis. The aim is to evaluate the methods of diagnostics and treatment of highly productive cows with ketosis in the natural and technogenic province of the Middle Urals. Experimental studies were carried out on the territory of the Sverdlovsk region. Research material - feed samples, fresh cows, biological material from highly productive cows (blood, urine, milk). Sample preparation and study were carried out by methods generally accepted in zoo technical and veterinary practice.The analysis revealed a concentrate type of feeding, an imbalance of the main nutrients (protein, sugar, fiber), a deficiency of essential trace elements (copper, cobalt, zinc, manganese), an excess of iron, the presence of heavy metals (nickel, lead, cadmium). All of these factors lead to the development of ketosis. On the farm, the disease is recorded in 13.6% of the number of calves. Ketosis manifests itself clinically (acetone odor of the skin and exhaled air, depression, immobility, decreased appetite to anorexia, cachexia, hypolactia and deterioration in milk quality, scar hypotension, hepatomegaly, liver tenderness, defecation disorder), hematologically (hypoproteinemia, hypoalbuminemia, hyperbiliminemia, hyperbiliminemia hypercreatininemia, hypoglycemia, hyperlactatemia, hyperketonemia and mineral imbalance), confirmed by the presence of ketone bodies in urine and milk.The complex treatment of cows in the experimental group included a long diet, pathogenetic, substitution, detoxification and physiotherapy. The control group was not detoxified. The treatment was carried out for 20 days, and dietary and physiotherapy - 45 days. Significant changes have been achieved in the experimental group. On the 20th day, the level of trace elements in the blood of cows increased, and iron and toxic elements decreased in comparison with the background. The concentration of glucose increased, ketone bodies - decreased, not reaching the norm. The concentration of serum lactate, AST, bilirubin indicates incomplete recovery of the liver. The therapy carried out in the experimental groups has a positive effect, but does not lead to a complete recovery of the cows with ketosis.