Open AccessMetabolic blood parameters of pigs of different age groups in the pathogenesis of nonspecific bronchopneumonia
Author(s) -
А. П. Шафиев
Publication year - 2021
Publication title -
voprosy normativno-pravovogo regulirovaniâ v veterinarii
Language(s) - English
Resource type - Journals
ISSN - 2072-6023
DOI - 10.52419/issn2072-6023.2021.4.81
Subject(s) - bronchopneumonia , physiology , medicine , population , hypoxemia , incidence (geometry) , immunology , biology , pathology , physics , environmental health , optics
Despite the sufficient amount of antimicrobial drugs and specific therapy and prevention, the proportion of respiratory diseases in pigs is still quite high [2, 5, 6, 13]. In some farms, the incidence, as well as post-slaughter changes in the lungs, can reach up to 100%. At the same time, mortality is usually insignificant. The main damage among the pig population consists of an economic component - it is the culling of slaughter products, a decrease in weight gain, low conversion of feed, carrying out therapeutic and preventive measures. There is evidence of hypoxemia and hypoxia developing against this background, which can lead to the development of acidosis, a decrease in the barrier properties of organs and tissues and the development of organopathologies. The previously obtained data on immunological blood tests allow us to talk about the suppression of innate and adaptive immunity in nonspecific bronchopneumonia [2, 4, 5, 6, 12, 13]. The purpose of this work was to conduct biochemical studies to study the state of metabolic parameters of the blood of pigs of different age groups, patients with nonspecific bronchopneumonia.The research was carried out at one of the large pig farms in the North-Western region of Russia and at the Department of Pathophysiology of the St. Petersburg State Medical University.As a result of studies in all experimental groups of animals, the effect of nonspecific bronchopneumonia on biochemical processes in piglets was established. In all sick animals, a noticeable decrease in the content of total protein, albumins and globulins was found, which can lead to inhibition of the function of protective mechanisms, and from all links of immunity (innate and adaptive). At the same time, the activity of alkaline phosphatase and lactate dehydrogenase enzymes was established in sick piglets, which indicates the generalization of the process with liver damage and the development of acidosis.