Changes in blood biochemical parameters in the first two months of lactation in primiparous goats of the saanen breed

The biochemical blood profile is one of the tools for monitoring the feeding and keeping of animals, and their state of health. However, it requires clarification for individuals reared both in different climatic conditions and operated under different housing systems. In this regard, the purpose of our study was to assess the temporal changes in the levels of circulating metabolites and the activity of enzymes in the first-flowing Saanen goats in the first two months of lactation, reared with intensive maintenance technology in the climatic conditions of the North-West region of Russia. Blood sampling from primiparous goats (n = 32) was carried out twice: on days 20- 30 and days 50-60 after lambing (MayJune). In the blood serum, the concentration of total protein, albumin, urea, creatinine, glucose, total cholesterol was determined, as well as the activity of enzymes: aspartate aminotransferase (AST), alanine aminotransferase (ALT) and alkaline phosphatase (ALP). It was found that by the end of the second month of lactation, the most significant changes occurred in lipid metabolism. Thus, the concentration of triglycerides and cholesterol in the blood increased by 71% and 11% (p˂ 0.001). The change in the parameters of protein metabolism was less dynamic: the content of total protein, creatine and albumin increased by 7.4%, 10.8% (p˂ 0.001) and 2% (p˂ 0.05), respectively. ALT activity increased by 19% (p˂ 0.001). Comparative analysis of blood biochemical parameters of the first and second months of lactation showed a positive dynamics of the process of adaptation of primiparous goats. The obtained values of blood biochemical parameters can be used to establish basic physiological values for 1-2 months of lactation in primiparous goats. This will facilitate a realistic assessment of the management, nutrition and health status of Saanen goats reared in large livestock facilities.