Open AccessPROSPECTS FOR THE USING OF SILICON-CONTAINING COMPOUNDS IN THE TECHNOLOGY OF IN VITRO MATURATION OF ANIMAL OOCYTES
Author(s) -
T. I. Kuzmina,
D. N. Tatarskaya,
Viacheslav Kravtsov
Publication year - 2021
Language(s) - English
Resource type - Conference proceedings
DOI - 10.52419/3006-2021-2-129-131
Subject(s) - somatic cell , in vitro , oocyte , embryo , biology , andrology , genotoxicity , microbiology and biotechnology , germ cell , chemistry , genetics , toxicity , medicine , gene , organic chemistry
In vitro production of animal embryos is an important tool for solving male and female infertility problems in animals. Modeling of extracorporeal maturation systems of oocytes using siliconcontaining compounds in the composition of culture media revealed the peculiarities of the realization of their effects on somatic and germ cells of ovarian follicles, depending on the structure. Highly dispersed silica nanoparticles (nHDS) positive effects on the fertility of female gametes in Bos Taurus and Sus Scrofa Domesticus. The gel substrate of silica (silicon dimethylglycerolate - DMGC) does not cause an increase in the level of embryos cleavage, while it does not have cytoand genotoxicity when tested on somatic and germ cells of antral follicles.Key words: siliconcontaining compounds, in vitro maturation, animal oocytes.