Open AccessEvaluation of in-vitro Anti-Inflammatory Activity of Gallic Acid
Author(s) -
Raksha Agrawal,
Aditya Ganeshpurkar,
Megha Verma
Publication year - 2021
Publication title -
international journal of research and review
Language(s) - English
Resource type - Journals
eISSN - 2454-2237
pISSN - 2349-9788
DOI - 10.52403/ijrr.20211240
Subject(s) - gallic acid , denaturation (fissile materials) , chemistry , albumin , in vitro , egg albumin , biochemistry , serum albumin , chromatography , nuclear chemistry , antioxidant
Gallic acid's anti-inflammatory effect was studied at various concentrations, including 50,100,150,200, and 250 ug/ml. Gallic acid's anti-inflammatory effect was assessed using two in-vitro assays: proteinase inhibition and albumin denaturation. The greatest proteinase inhibition activity of 52.83 percent was achieved at a concentration of 250ug/ml, according to the results. It also revealed that at 250ug/ml, the maximum percentage inhibition in albumin denaturation was 74.79 percent. Gallic acid's antiproteinase and albumin denaturation activities both increase with increasing concentrations, according to this research.Keywords: Gallic acid, Anti-Inflammatory, In-Vitro Assays, Albumin Denaturation, Proteinase activity.