Open AccessAssociation of Acute Lymphoblastic Leukemia with Unilateral Facial Palsy: A Rare Presentation
Author(s) -
Vipul Taneja,
Goud Raghvendra,
Kusum Mahajan
Publication year - 2021
Publication title -
international journal of health sciences and research
Language(s) - English
Resource type - Journals
ISSN - 2249-9571
DOI - 10.52403/ijhsr.20210811
Subject(s) - medicine , immunophenotyping , lymphoblastic leukemia , leukemia , risk stratification , bone marrow , oncology , chemotherapy , presentation (obstetrics) , flow cytometry , immunology , surgery
Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer. Survival probability of pediatric ALL had been 10-20%, but the most recent clinical trials with multiagent chemotherapy have achieved overall survival probability of better than 80%. This is achieved because of better supportive care, treatment stratification based on relapse risk, and the biological features of leukemic cells. Diagnosis of ALL was based principally on morphological identification of leukemic blasts in bone marrow, and immunophenotype assessment by flow cytometry is necessary, and most pediatric ALL cases are clinically classified as B-cell precursor, T-cell ALL, or mature B-cell types.Key words: Acute Lymphoblastic Leukemia, ALL, Unilateral Facial palsy, pediatric ALL.