Open AccessTHE SIGNIFICANCE OF THE STUDY OF THE LIVER FUNCTION TEST WITHIN POST-TRANSPLANT PATIENTS
Author(s) -
Merab Nakashidze,
Zurab Chikhladze,
David Kobuladze,
David Beridze
Publication year - 2021
Publication title -
ek'sperimentuli da klinikuri medic'ina
Language(s) - English
Resource type - Journals
ISSN - 1512-0392
DOI - 10.52340/jecm.2021.556
Subject(s) - alkaline phosphatase , medicine , liver transplantation , bilirubin , liver function tests , gastroenterology , albumin , liver function , gamma glutamyltransferase , alanine aminotransferase , transplantation , biology , biochemistry , enzyme
In recent years, the survival rate of patients after liver transplantation (LT) has improved significantly. However, successful transplantation is directly related to the proper management of the patient after surgery, including considering essential aspects based on the results of laboratory tests. Therefore, it is essential to study the laboratory characteristics to investigate the functional state of the liver. In the present study, we investigated the indicators of liver function in postoperative patients: alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), albumin, total bilirubin, gamma-glutamyl transferase (GGT). Venous blood samples were used for investigation. A total of 10 post-transplant patients were studied. Appropriate research methods were used. P<0.05 was considered statistically significant. Overall, our results have shown that intensive examinations of the liver panel in postoperative patients significantly contribute to the proper management of the complicated patient, which directly impacts the final results. Notably, the variability of GGT and ALP may be directly related to the transplanted chronic immune response of the liver and may be used as an early marker for the diagnosis of biliary complications.