Open AccessCHARACTERIZATION OF INTRATONZILLAR REGIONAL DISTRIBUTION CD20+ B LYMPhOCYTES IN DENTAL CARIES
Author(s) -
Z Vadachkoria,
George Kipiani,
Omar Khardzeishvili
Publication year - 2021
Language(s) - English
DOI - 10.52340/csw.2021.566
Subject(s) - cd20 , monoclonal antibody , b cell , antigen , distribution (mathematics) , medicine , antibody , immunology , mathematics , mathematical analysis
Employing а series of monoclonal antibodies directed against B cell subsets using the streptavidin-biotin complex method. We have studied the distribution of immunocompetent cells in sections of tonzills from 64 patients with inammatory disease and dental caries. The following conclusion can he made inregard to our study. The persentage of CD20+ B limfocytes decreases in all compartments of tonzils with increasing caries activity. The reason for this may depend on a change of limfokine profiles produced by the angaged antigen presenting cells and T-cell subsets.