Open AccessInfluence of Age and Type 1 Diabetes Mellitus on Serological Test for Celiac Disease in Children
Author(s) -
Anshu Maheshwari,
Zhaoping He,
Melissa Weidner,
Patrick S. Lin,
Ryan Bober,
Fernando del Rosario
Publication year - 2021
Publication title -
pediatric gastroenterology, hepatology and nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.44
H-Index - 19
eISSN - 2234-8646
pISSN - 2234-8840
DOI - 10.5223/pghn.2021.24.2.218
Subject(s) - tissue transglutaminase , serology , type 1 diabetes , medicine , histology , gastroenterology , antibody , cutoff , immunology , diabetes mellitus , endocrinology , biology , biochemistry , physics , quantum mechanics , enzyme
Serological tests of tissue transglutaminase (TTG) and deamidated gliadin (DGP) antibodies for celiac disease diagnosis show conflicting correlation with histology in young children and in type 1 diabetes mellitus (T1DM). Tests' ability to predict histology and cutoff values based on age and T1DM was evaluated.