Open AccessIs There Any Other Disease Under The New Diagnosis of Diabetes That Is Difficult To Control?
Author(s) -
Muhammed Ali Kaypak,
Damla Çağla Patıe,
Faruk Ӧzalp,
Harun Akar
Publication year - 2021
Publication title -
i̇zmir tepecik eğitim hastanesi dergisi
Language(s) - English
Resource type - Journals
eISSN - 1305-7146
pISSN - 1305-7073
DOI - 10.5222/terh.2021.94840
Subject(s) - acromegaly , medicine , growth hormone , diabetes mellitus , endocrinology , insulin resistance , pituitary adenoma , differential diagnosis , disease , hormone , muscle hypertrophy , adenoma , pathology
High levels of growth hormone and insulin-like growth factor 1 contribute to tissue proliferation and hypertrophy in patients with acromegaly mostly due to growth hormone-secreting pituitary adenoma. Some phenotypic features of acromegaly that make us to consider in the differential diagnosis are excessive growth of the hands and feet and coarsening facial features. Growth hormone also induces lipolytic activities and insulin resistance, so patients with acromegaly often present with impaired glucose tolerance and type 2 diabetes mellitus. We wanted to share a case with treatment-resistant hyperglycemia which is the cause of presentation of acromegaly.