Open AccessCan Preoperative Neutrophil-Lymphocyte Ratio and Platelet-Lymphocyte Ratio Predict Systemic Inflammatory Response Syndrome That Develops After Percutaneous Nephrolithotomy?
Author(s) -
Uygar Miçooğulları,
Orçun Çelik,
Mehmet Çağlar Çakıcı,
Erdem Kısa,
Cem Yücel,
Okan Nabi Yalbuzdağ,
Mehmet Yoldaş,
Hakan Üçok,
Tufan Süelözgen,
Mehmet Keskın,
Yusuf Özlem İlbey
Publication year - 2021
Publication title -
i̇zmir tepecik eğitim hastanesi dergisi
Language(s) - English
Resource type - Journals
eISSN - 1305-7146
pISSN - 1305-7073
DOI - 10.5222/terh.2021.38980
Subject(s) - medicine , systemic inflammatory response syndrome , neutrophil to lymphocyte ratio , univariate analysis , gastroenterology , logistic regression , multivariate analysis , mean platelet volume , lymphocyte , creatinine , surgery , platelet , sepsis
Objective: First objective of this study was to find out factors influencing development of postoperative systemic inflammatory response syndrome (SIRS) after percutaneous nephrolithotomy (PNL). Secondary objective was to point out the role of preoperative neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) in SIRS estimation. Method: The data of 756 patients that underwent PNL for kidney stones between 2012 and 2019 were evaluated retrospectively. Patients were divided into 2 groups as non-SIRS and SIRS group. The effects of NLR, PLR and other operative and demographic variables on development of SIRS were investigated. Multivariate logistic regression analysis that was performed on variables that were significant in the univariate analyses was used to establish independent risk factor for post-PNL SIRS. Results: Univariate analysis revealed a significant association between presence of SIRS and preoperative PLR (p 120.5, NLR >2.75, and blood transfusions should be monitored closely due to the possible development of serious complications.