Open AccessAcute Proximal Tubular Necrosis Due to Cidofovir Usage in BK Virus Related Hemorrhagic Cystitis in an Allogeneic Stem Cell Transplanted Patient
Author(s) -
Şebnem İzmir Güner,
Mustafa Teoman Yanmaz,
Ekrem Güner,
Pınar Seymen,
Melike Nalbant Moray,
I. Kilicarslan
Publication year - 2021
Publication title -
grand journal of urology
Language(s) - English
Resource type - Journals
ISSN - 2757-7163
DOI - 10.5222/gju.2021.25743
Subject(s) - cidofovir , hemorrhagic cystitis , bk virus , medicine , transplantation , complication , virology , virus , hematopoietic stem cell transplantation , surgery , kidney transplantation
Hemorrhagic cystitis (HS) is a frequently seen complication of bone marrow transplantation. This condition occurs depending on the preparatory regimen of bone marrow transplantation. The BK virus (BKV), a human polyomavirus, is a small double helix DNA virüs belonging to the Papovaviridae family. It is commonly found in societies as an occult infection. Whereas, cidofovir (CDV), an acyclic nucleoside phosphonate, is used as a proven antiviral agent against polyomaviruses. In this case report, acute proximal tubular necrosis due to cidofovir used in hemorrhagic cystitis caused by BK virus, and its treatment in a patient diagnosed with T-lymphoblastic lymphoma in remission, and underwent allogeneic stem cell transplantation, was presented.