Open AccessSEROLOGICAL CONFIRMATION OF MEASLES IN CHILDREN ADMITTED WITH CLINICAL DIAGNOSIS OF MEASLES.
Author(s) -
Israr Ul Haq,
Arif Ahmed,
Muhammad Ali Jan,
Ihsan Ul Haq,
Muhammad Amjad Bashir
Publication year - 1969
Publication title -
journal of saidu medical college
Language(s) - English
Resource type - Journals
ISSN - 1819-4583
DOI - 10.52206/jsmc.2012.2.1.127-130
Subject(s) - measles , medicine , serology , vaccination , pediatrics , rubella , antibody , immunology
Objective: To determine the frequency of IgM antibodies in clinically diagnosed cases of measles.Design: Cross-sectional, descriptive studyPlace and duration: Department of Pediatrics, Saidu Group of Teaching Hospital, Saidu Sharif, Swat(from 1st Jan 2010-31 Dec 2011).Patients and method: A total of 150 patients of measles clinically diagnosed were enrolled for the study.Detailed history, demographic profile and vaccination status were recorded. Blood samples were collectedfrom all subjects for measles serology by observing WHO protocol.Results: Out of 150 patients, 57% (86) were male and 43% (64) were female with mean age of 38.28±30.99months. Out of these 150 patients, 66% (99) were positive for measles IgM antibodies, while 34% (51) werenegative for measles IgM. Out of 51 measles negative patients 11.8% (6) were positive for rubella.Conclusion: Diagnosing measles on clinical features alone is reasonable but not specific and IgM may beused to confirm the diagnosisKey words: Measles, IgM antibodies, children, vaccination status