Open AccessRESEARCH CHARACTERISTICS HISTOPATHOLOGY AND APPLICATION IMMUNOHISTOCHEMISTRY TO CLASSIFY NON-HODGKIN LYMPHOMA IN 103 MILITARY HOSPITAL
Author(s) -
Nguyễn Khắc Tuyến,
Trần Ngọc Dũng
Publication year - 2021
Publication title -
y học cộng đồng
Language(s) - English
Resource type - Journals
ISSN - 2354-0613
DOI - 10.52163/jcm.v62i2.40
Subject(s) - lymphoma , medicine , histopathology , malignancy , immunohistochemistry , disease , non hodgkin's lymphoma , lymph node , pathology , oncology
Objective: Evaluate the macroscopic and microscopic characteristics of Non-Hodgkin's lymphoma. Application of the manifestation of immune markers to classification Non-Hodgkin's lymphoma. Matherial and Method: The cross-sectional descriptive, retrospective and prospective study of 75 patients diagnosed on histopathology and immunohistochemistry as Non-Hodgkin's lymphoma at Military Medical Hospital 103 from January 2018 to September 2020. Results: The disease occurred in men more than women: 2/1. The average age of diseases is 58.31 ± 17.62. Non-Hodgkin's lymphoma in the lymph node accounts for the highest proportion (57.3%). WF7 accounts for the highest percentage (54.7%). The majority of the disease is in intermediate malignancy with 76%. B-cell Non-Hodgkin's lymphoma accounts for 84%. Diffuse large B-cell lymphoma accounts for the highest rate of 66.67%, of which the GCB type accounts for 32%, the non-GCB accounts 68%. Conclusion: The diagnosis and classification of Non Hodgkin lymphoma helps clinicians predict the response to chemotherapy, extra life, which is indicative of monoclonal antibody therapy