Open AccessTreatment of Alzheimer’s disease by natural products
Author(s) -
Sana Chougle,
Dinesh Kumar,
Andleeb Khan,
Sadaf Zehra,
Ali Ahmad
Publication year - 2021
Publication title -
deneysel ve klinik tıp dergisi/journal of experimental and clinical medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.103
H-Index - 3
eISSN - 1309-4483
pISSN - 1309-5129
DOI - 10.52142/omujecm.38.4.42
Subject(s) - galantamine , donepezil , disease , dementia , medicine , neuroprotection , natural compound , intensive care medicine , psychiatry , pharmacology , biochemical engineering , engineering
Alzheimer’s disease is a neurological disorder that progressively affects the brain cells. It is sometimes accompanied with dementia and commonly seen in elderly people. It ultimately leads to impaired cognitive functions and loss of memory. Widely used drugs such as donepezil and galantamine successfully abate mild to moderate symptoms of the disease though they have profound side effects. Natural products have been a source of medicine for over thousands of years. Plant secondary metabolites such as alkaloids, flavonoids, terpenoids, etc. are major sources of such medicines. In recent times, the use of natural products to treat various diseases has gained a lot of popularity. Extensive research is being undertaken to identify and isolate various natural products that can be used to not only reduce the disease symptoms but also as a permanent cure. The review article aims to summarize the effects of various natural products and their neuroprotective mechanisms that can be helpful to cure Alzheimer’s disease.