Open AccessCHANGES IN HUMAN EPITHELIAL TISSUE IN CHRONIC ALCOHOL INTOXICATION AND ADVERSE ENVIRONMENTAL CONDITIONS IN THE AGE ASPECT. PARTICIPATION OF MORPHOFUNCTIONAL ZONES AND SRC KINASE IN THIS PROCESS
Author(s) -
T. M. Yavisheva,
С. Д. Щербаков
Publication year - 2021
Publication title -
chronos journal
Language(s) - English
Resource type - Journals
ISSN - 2658-7556
DOI - 10.52013/2658-7556-53-3-3
Subject(s) - pathological , proto oncogene tyrosine protein kinase src , organism , kinase , age groups , alcohol , physiology , biology , microbiology and biotechnology , pathology , medicine , biochemistry , demography , genetics , sociology
The reaction of human epithelial tissue to the effects of various pathological agents mainly depends on both the total amount of key protein in the organism – Src-kinase and the quantity of its active and inactive portions. In the age aspect, there is a decrease in Src-kinase content in the human body. The epithelial tissue of two age groups: 20-40 and 75 years and older responds most vigorously to pathological effects, including the entering of viruses, since in 20-40 years the number of Src-kinases is the largest of all age groups, and 75 years and older — the smallest. Under conditions of pathology, this leads to a decrease in the reactivity of organism tissues at 20-40 years and hyperactivity at 75 years and older.