Open AccessESTIMATION OF THE INFLUENCE OF DIFFERENT METHODS OF ADMINISTRATION OF METHYLETHYLPYRIDINOL HYDROCHLORIDE (EMOXIPIN) ON ELIMINATION OF THE PATHOLOGY OF THE MICROCIRCULATORY BREED IN TRAUMATIC LESIONS OF LIMB MUSCLES
Author(s) -
D.G. Tereshko,
А. П. Трухан,
Т. А. Letkovskaya
Publication year - 2021
Publication title -
voennaâ medicina
Language(s) - English
Resource type - Journals
ISSN - 2074-5044
DOI - 10.51922/2074-5044.2021.2.37
Subject(s) - medicine , breed , pathology , intraperitoneal injection , intramuscular injection , anesthesia , pharmacology , biology , genetics
In this article, the authors reflect the results of experimental studies devoted to the study of traumatic lesions of limb muscles in laboratory animals. The effect of different routes of administration (intraperitoneal and intramuscular paravulnary) of methylethylpyridinol hydrochloride (emoxypine) on the state of the microvasculature was evaluated. In the course of the experiment, it was found that intramuscular paravulnar administration of emoxipin makes it possible to more effectively eliminate the pathology of the microvasculature in comparison with the intraperitoneal route of administration. Also, as a result of the studies, it was noted that the MSB staining method is the most appropriate in terms of fibrin differentiation and assessment of the state of the microvasculature. The data obtained will make it possible to develop new approaches in the treatment of traumatic lesions of the limb muscles.