Open AccessBiotherapic 200dH is harmful to acute murine infection with Trypanosoma cruzi.
Author(s) -
Denise Lessa Aleixo,
Fabiabarro Ferraz,
Guilherme Conte Diniz,
Marcelo Augusto de Lima Rodrigues,
Silvana Marques de AraÃojo
Publication year - 2021
Publication title -
international journal of high dilution research
Language(s) - English
Resource type - Journals
ISSN - 1982-6206
DOI - 10.51910/ijhdr.v16i2.824
Subject(s) - trypanosoma cruzi , chagas disease , trypanosoma , biology , benznidazole , trypanosomiasis , medicine , immunology , virology , parasite hosting , world wide web , computer science
Biotherapics employed to treat mice infected by Trypanosoma cruzi were carried out with encouraging results. The aim of this study was evaluated the effect of biotherapic of Trypanosoma cruzi 200dH, using two different schedules of treatment. Swiss male mice, aged 56 days-old were infected intraperitonealy with 1,400 blood trypomastigotes of Trypanosoma cruzi Y strain and were divided into groups: C.I.- infected animals, E.D. – Infected animals treated from the day 1 until the end of the experiment; 200dH S.D. – Infected animals treated on the day 1. Parasitological, clinical and immunological parameters were evaluated. The group of animals that received the medicine in a single dose presented higher value to total parasitaemia and lower value of pre patent period compared to control untreated group (p