THE EFFECTS OF EUGLVCEMIC INSULIN CLAMP ON THE METABOLISM OF 3-HYDROXVBUTYRATE AND PLASMA FREE FAHY ACIDS BY THE HIND LIMB OF LACRATING SHEEP | Zendy

A. J. A OSUAGWUH | Zendy; R. Smithard | Zendy; J. Metcalfe | Zendy; T. E. C. Weekes | Zendy

Open Access

THE EFFECTS OF EUGLVCEMIC INSULIN CLAMP ON THE METABOLISM OF 3-HYDROXVBUTYRATE AND PLASMA FREE FAHY ACIDS BY THE HIND LIMB OF LACRATING SHEEP

Author(s) -

A. J. A OSUAGWUH,

R. Smithard,

J. Metcalfe,

T. E. C. Weekes

Publication year - 2021

Publication title -

nigerian journal of animal production

Language(s) - English

Resource type - Journals

ISSN - 0331-2062

DOI - 10.51791/njap.v15i.965

Subject(s) - hindlimb , insulin , medicine , endocrinology , metabolism , chemistry , plasma glucose , biology

The effects of exogenous insulin, with euglycemia, on the concentration differences, extraction ratio and uptake of 3- hydroxybutyrate and plasma free fatty acids by the lactating sheep hind limb were studied. Generally, the results showed that with increasing plasma insulin levels, while maintaining euglycemia, the concentrations, arterio-venous concentration differences, extraction ratio and uptake of 3-hydrubutyrate and free fatty acids Were significantly (P<0.05) reduced, but Significant correlation was established between arterial concentration of 3-hydtoxvbutyrate and plasma free fatty acids and their uptake. A similar relationship was also obtained between the arterial concentrations of 3-hydroxybutyrate plasma free fatty acids.

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