Post-traumatic pituitary impairment in traumatic brain injury patients

Traumatic brain injury (TBI) is a major cause of death and disability for the young adult population. The total annual incidence of hospitalized TBIs depends on the region, periods and measurement methods. In fact, each year, nearly 69 million people suffer head injuries, which represents a worldwide incidence of 939 cases per 100,000 people for all causes and severities., Each year, 55.9 million people (740 cases per 100,000 people) suffer from mild traumatic brain injury, while severe cases on the other hand represent 5.48 million cases (73 cases per 100,000 people). Post-traumatic pituitary impairment is a complication that can often occur in association with a TBI. Its actual prevalence remains difficult to assess because the published studies are heterogenous and also because of the difficulty to interpret the results of hormone tests in this specific population. The epidemiological study of head trauma patients makes it possible to measure the quantitative aspect in terms of incidence, to establish a screening of the situation in a vital emergency department (VED), to identify the risk factors to better target preventive actions, and to study the short-term and long-term hormonal changes in this population. Our study is a retrospective analysis of a series of 399 head trauma patients admitted to the VED between January 2017 and December 2020 and will initially focus on describing the epidemiological profile of this population. Keywords:  Traumatic brain injury, Post-traumatic pituitary impairment, epidemiology.