
Temperature Management in Patients After Cardiac Arrest
Author(s) -
Diksha Kumar,
Khai Tran,
Zahra Premji
Publication year - 2022
Publication title -
canadian journal of health technologies
Language(s) - English
Resource type - Journals
ISSN - 2563-6596
DOI - 10.51731/cjht.2022.265
Subject(s) - targeted temperature management , medicine , hypothermia , randomized controlled trial , intensive care medicine , clinical trial , emergency medicine , resuscitation , cardiopulmonary resuscitation , return of spontaneous circulation
Two systematic reviews (1 with a network meta-analysis and 1 with a meta-analysis), 1 randomized controlled trial, and 7 non-randomized studies were identified about the comparative clinical effectiveness of normothermia versus hypothermia in adult patients after cardiac arrest.
Normothermia was found to be similar to hypothermia for several clinical- and patient-related outcomes, such as survival, hospital mortality, and quality of life. There was limited evidence to suggest that either type of targeted temperature management was more efficacious, with findings suggesting that normothermia may be associated with greater protocol adherence and decreased prescription medication use coming from low-quality non-randomized studies.
Four evidence-based guidelines were identified regarding targeted temperature management (normothermia or hypothermia) in adult patients after cardiac arrest. All guidelines strongly recommend targeted temperature management for eligible patients, particularly for patients resuscitated following out-of-hospital cardiac arrest. Identified guidelines from the Canadian Cardiovascular Society and American Academy of Neurology present strong recommendations for hypothermic targeted temperature management.