Open AccessPoint-of-Care Testing and N-Acetylcysteine for Acute Acetaminophen Overdose
Author(s) -
Khai Tran,
Jennifer Horton
Publication year - 2021
Publication title -
canadian journal of health technologies
Language(s) - English
Resource type - Journals
ISSN - 2563-6596
DOI - 10.51731/cjht.2021.105
Subject(s) - acetylcysteine , acetaminophen , acetaminophen overdose , medicine , regimen , point of care , acute care , emergency medicine , end point , intensive care medicine , anesthesia , health care , surgery , nursing , chemistry , computer science , biochemistry , real time computing , economics , antioxidant , economic growth
Evidence on the clinical utility and cost-effectiveness of point-of-care devices could not be identified.
Two evidence-based guidelines recommend a 2-bag regimen of N-acetylcysteine, consisting of both a loading dose and maintenance dose, administered by IV for patients with acute acetaminophen overdose.