Open AccessA Continuing Quest for an Acceptable Alternative Sickle Cell Anaemia (SCA) Severity Scoring System in a Resource-Constrained Setting
Author(s) -
Aliyu Dahiru Waziri,
Sani Awwalu,
Ismaila Nda Ibrahim,
Ibrahim Usman Kusfa,
Aishatu Maude Suleiman,
Abdulaziz Hassan
Publication year - 2020
Publication title -
annals of basic and medical sciences
Language(s) - English
Resource type - Journals
ISSN - 2782-7542
DOI - 10.51658/abms.202011.5
Subject(s) - scoring system , medicine , white blood cell , anemia , sickle cell anemia , severity of illness , blood count , intensive care medicine , disease
Background: Sickle cell Anaemia (SCA) severity scoring has remained challenging. Scoring systems based on clinical and certain laboratory parameters are limited in simplicity and wide applicability. This is further worsened by dearth of exhaustive and accurate patient history. This study compared a simple, laboratory parameter-based severity scoring system to a pre-existing scoring system. Methodology: Derivation group (n = 45) and validation group (n = 300) were enrolled during steady state. Complications, haemoglobin (Hb) concentration and white blood cell counts (WBC) were documented. Severity scores were computed for each participant based on number of complications, Hb and WBC counts using a preexisting scoring system. Proposed scoring system