Open AccessASSESSMENT OF THE FREQUENCY OF DIFFERENT PATTERNS OF CLINICAL PRESENTATION OF CHILDREN PRESENTING WITH CONGENITAL ADRENAL HYPERPLASIA
Author(s) -
Habib Ullah,
Fayiza Manzoor Ahmad,
Sumaira Hmaid,
Noor ul Ain Mehak,
Assiya Afzal,
Saqib Munir
Publication year - 2021
Publication title -
pakistan postgraduate medical institute
Language(s) - English
Resource type - Journals
ISSN - 2710-1924
DOI - 10.51642/ppmj.v31i04.388
Subject(s) - virilization , congenital adrenal hyperplasia , medicine , sex organ , pediatrics , presentation (obstetrics) , population , obstetrics , gynecology , biology , androgen , environmental health , hormone , genetics
Objective: To assess the frequency of different patterns of presentation of children presenting with congenital adrenal hyperplasia.
Methodology:It was a cross sectional study conducted at the department of Pediatric, Fatima Memorial Hospital, Lahore, from19-12-2017 to 19-06-2018.92 infants who met the selectin criteria were recruited for the study. Then blood sample was obtained and if serum sodium <135mEq/L, then salt depletion was labeled. Then, infants underwent genital examination for assessment of genital virilization. All data is entered is specially designed Performa and analyzed in SPSS.
Results: The mean age of patients was 6.52±3.56months. There were 49 (53.26%) male while 43 (46.74%) female infants. The mean weight of patients was 5.59±1.44kg. There were 21 (22.83%) cases of consanguineous marriage while 71 (77.17%) were other than cousin marriage. There were 63 (68.48%) had salt depletion while in 29 (31.52%) did not had salt depletion. There were 39 (42.39%) had genital virilization while in 53 (57.61%) did not had genital virilization.
Conclusion: Thus the frequency of patterns (salt depletion and genital virilization) of Congenital adrenal hyperplasia are high in local population.