PREPARATION OF STABLE COMPOSITES WITH NANOPARTICLES OF METALS IN BIOMEDICAL MATRICES

The unique properties of metal nanoparticles are increasingly used in the pharmaceutical, medical, food, textile and paint industries. It is known that the properties of nanoparticles depend on the shape, size, concentration. Agglomeration processes that occur during the production and storage of nanoparticles lead to a reduction in the size of the specific area to the volume of nanoparticles, which in turn leads to the loss of the unique properties of nanoparticles. In the process of analysis of domestic and foreign literature it was found that the problem of agglomeration processes of nanoparticles is relevant. One of the possible approaches to solving the agglomeration of synthesized nanoparticles, which is proposed in this work is the use of matrices of carriers. In this case, the matrix can be liquids: monomers, oils of vegetable origin or medical substances that are constituent tablets, capsules, ointments, soaps, and paints.The morphology, size, structure and time stability of silver and copper nanoparticles in the obtained dispersed systems were studied. Examples of stability of composites based on glycerol, polytetrahydrofuran (PTGF), oils of synthetic and vegetable origin with nanoparticles of metals with a size of 15… 52 nm are presented. The stability of dispersed systems has been improved through the use of two approaches: the use of surfactants and dispersed systems based on matrices with low crystallization temperature