Open AccessChanges of the Biochemical Parameters of the Blood Serum of Wistar rats Exposed to Chronic Stres
Author(s) -
К. А. Кидун,
Alexander Litvinenko,
Т. С. Угольник,
Н. М. Голубых,
Е. К. Солодова
Publication year - 2019
Publication title -
problemy zdorovʹâ i èkologii
Language(s) - English
Resource type - Journals
eISSN - 2708-6011
pISSN - 2220-0967
DOI - 10.51523/2708-6011.2019-16-4-12
Subject(s) - medicine , uric acid , endocrinology , chronic stress , blood serum , cholesterol
Objective: to assess the effect of chronic nonspecific stress on changes of the biochemical parameters of the blood serum in male Wistar rats. Material and methods. The experimental study was performed on sexually mature male Wistar rats. The experimental group (n = 71) was exposed to chronic nonspecific stress according to the Ortiz method. The control group of the animals included intact animals (n = 31). Results. The study has revealed changes in the biochemical composition of the blood serum of the rats: increased activity of ALT, LDH, ALP, urea, uric acid, and cholesterol, a decreased level of triglycerides. Conclusion. These changes may indicate the alteration of the level of the intensity of the physiological processes of energy supply in the conditions of chronic stress.