Open AccessTHE IMMUNOHISTOCHEMICAL ASSESSMENT OF THE CHARACTER OF LYMPHOID INFILTRATION IN VARIOUS FORMS OF THYROID PATHOLOGY
Author(s) -
К. М. Бутолина,
S. А. Lyalikov,
V. А. Basinsky,
Т. Т. Shtabinskaya,
V. S. Aleksinsky,
А. . Маршалэк
Publication year - 2017
Publication title -
problemy zdorovʹâ i èkologii
Language(s) - English
Resource type - Journals
eISSN - 2708-6011
pISSN - 2220-0967
DOI - 10.51523/2708-6011.2017-14-4-5
Subject(s) - pathology , thyroid , medicine , goiter , immunohistochemistry , thyroiditis , euthyroid , autoimmune thyroiditis , infiltration (hvac) , endocrinology , physics , thermodynamics
Objective: to characterize the phenotype of lymphocytes in lymphoid infiltrates in various forms of thyroid pathology. Material and methods . The operating material of 112 cases of thyroid diseases has been studied. The immunohistochemical examination using monoclonal antibodies to the antigens CD3, CD4, CD1α, CD23, CD25, CD8 and TGF-β has been conducted. Results. The quantitative assessment of lymphocyte subpopulations in lymphoid infiltrates in the tissue of the thyroid gland in thyrotoxic goiter, autoimmune thyroiditis, nodular euthyroid goiter, and thyroid cancer has been given.