Open AccessAtomic force microscopy of cells as a method for the study of the pathogenesis and AS THE basis for the development of methods of DISEASE DIAGNOSIS
Author(s) -
М. Н. Стародубцева
Publication year - 2017
Publication title -
problemy zdorovʹâ i èkologii
Language(s) - English
Resource type - Journals
eISSN - 2708-6011
pISSN - 2220-0967
DOI - 10.51523/2708-6011.2017-14-4-21
Subject(s) - atomic force microscopy , nanotechnology , nanoscopic scale , surface (topology) , cell , materials science , disease , pathogenesis , microscopy , cell mechanics , development (topology) , chemistry , medicine , pathology , mathematics , biochemistry , geometry , cytoskeleton , mathematical analysis
The application of atomic force microscopy (AFM) for the study of micro- and nanoscale areas of the cell surface allows researchers to introduce new cell parameters and to obtain qualitatively new notions about the causes and mechanisms of changes of the cell properties. The aim of the work was to assess the prospects of AFM of cells using the example of blood cells for the study and development of new methods of disease diagnosis based on the specificity of AFM modes of operation and the recent AFM data on the cell surface properties.