Open AccessSERUM FERRITIN AS A PREDICTOR OF DIABETES MELLITUS TYPE 2 IN PATIENTS WITH CHRONIC HEPATITIS
Author(s) -
И. В. Пальцев,
А. Л. Калинин,
Е. Н. Сницаренко
Publication year - 2016
Publication title -
problemy zdorovʹâ i èkologii
Language(s) - English
Resource type - Journals
eISSN - 2708-6011
pISSN - 2220-0967
DOI - 10.51523/2708-6011.2016-13-2-13
Subject(s) - medicine , ferritin , diabetes mellitus , type 2 diabetes mellitus , gastroenterology , chronic hepatitis , etiology , odds ratio , serum iron , endocrinology , immunology , hemoglobin , virus
Objective: to analyze the possibility of the use of iron metabolism indicators (serum ferritin and serum iron) as predictors of diabetes mellitus type 2 in patients with chronic hepatitis. Material and methods. We have examined 120 patients with chronic hepatitis of various etiology and have assessed the possibility of the use of serum iron and serum ferritin in the diagnosis of diabetes . Results. We have received the data about the diagnostic value of iron metabolism indicators in detection of diabetes mellitus type 2. The sensitivity of serum ferritin in patients with chronic hepatitis at a point of separation of 234mkg/l was 66.7 %, the specificity was 73.9 %, AUC - 0.735 (95 % CI 0.643-0.815, р = 0.001). The odds ratio of the detection of diabetes mellitus type 2 for patients with high-level serum ferritin was 4.6 (95 % CI 1.6-13.6, р = 0.005). Conclusion. Serum ferritin has shown the highest prognostic value as a predictor of diabetes mellitus type 2 among the indicators of iron metabolism in the patients with chronic hepatitis.