Open AccessTHE PARAMETERS OF INTRAOCULAR PRESSURE RELATED TO DIFFERENT SCHEMES OF LOCAL HYPERTENSIVE THERAPY IN PATIENTS WITH PRIMARY OPEN-ANGLE GLAUCOMA (MULTICENTER STUDY)
Author(s) -
A.V. Kuroyedov,
Л. Д. Абышева,
R. V. Avdeyev,
A. S. Alexandrov,
A. S. Basinsky,
E. A. Blyum,
A. Yu. Brezhnev,
И. Р. Газизова,
А. Б. Галимова,
О. В. Гапонько,
V. V. Garkavenko,
А. М. Гетманова,
В. В. Городничий,
М. С. Горшкова,
A. A. Gusarevitch,
D. A. Dorofeyev,
С. А. Жаворонков,
P. Ch. Zavadsky,
А. Б. Захидов,
О. Г. Зверева,
У. Р. Каримов,
Anita Kulik,
С. Н. Ланин,
Jamilya N. Lovpache,
И. А. Лоскутов,
Е. В. Молчанова,
Н. А. Нефедов,
V. Yu. Ogorodnikova,
O. N. Onufrichuk,
E. Yu. Openkova,
S. Yu. Petrov,
Yu. I. Rozhko,
Т. А. Сиденко,
Л. Б. Таштитова,
Н. Е. Фомин,
М. С. Худжатова
Publication year - 2015
Publication title -
problemy zdorovʹâ i èkologii
Language(s) - English
Resource type - Journals
eISSN - 2708-6011
pISSN - 2220-0967
DOI - 10.51523/2708-6011.2015-12-2-5
Subject(s) - glaucoma , medicine , intraocular pressure , ophthalmology , open angle glaucoma , medical therapy , cornea
Objective: to study the intraocular pressure (IOP) in patients with primary open-angle glaucoma during the treatment with hypotensive drugs depending on age, medical history, stage of disease and the central thickness of the cornea. Material and methods. 812 right eyes of 812 patients were examined, 637 of 812 were glaucoma patients and 175 healthy people of the control group. Results. The level of the intraocular pressure was significantly higher in patients with severe glaucoma than in patients with moderate glaucoma or healthy people. There was no significant difference in the central corneal thickness between glaucoma patients and healthy people (both male and female). The IOP level was higher in the group of patients treated with non-fixed combination of beta-blockers and prostaglandins regardless of the disease stage. The IOP compensation was found in 69.9 % of patients with moderate glaucoma and 14.4 % of patients with severe glaucoma. Conclusion. The results of the study can be used as clinical guidelines for determination of the optimal IOP range while choosing the optimal IOP-lowering medications at the start of therapy and during the follow-up of patients with moderate and severe glaucoma.