Open AccessTHE INFLUENCE OF NEW ANTIBACTERIAL SUTURAL MATERIAL ON THE TRAUMATORY PROCESS IN EXPERIMENT
Author(s) -
А. С. Князюк,
А. Н. Лызиков,
Д. А. Зиновкин,
Э. А. Надыров,
Д. Н. Бонцевич
Publication year - 2015
Publication title -
problemy zdorovʹâ i èkologii
Language(s) - English
Resource type - Journals
eISSN - 2708-6011
pISSN - 2220-0967
DOI - 10.51523/2708-6011.2015-12-1-9
Subject(s) - antibiotics , medicine , surgery , biology , microbiology and biotechnology
Objective: to give morphological evaluation of the biologic effect of new antibacterial sutural material made of polyglycolic acid on tissues and organs. Material and methods: The surface of surgical sutures is modified by the method of direct radiation inoculation of acrylic acid and immobilization of the antibiotics Levofloxacin on it. The sutural material was implanted into the liver, intestine, uterus and anterior abdominal wall of outbred female white rats. The inflammation and tissue reaction was assessed according to the all Union State Standard (AUSS) R ISO 10993 «Medical product. Evaluation of biologic effect of medical products». Results. Using this new antibacterial sutural material reduces the number of infectious complications in post-operative period, tissue reaction to the implantation of modified sutural material is characterized by fewer inflammatory changes, absence of vulnerary infection, fewer fibrous changes in later post-implantation period, which suggests healing of such wounds by primary tension. Conclusion. The new sutural material with the antibacterial effect may be used in surgery while performing operative intervention to prevent any infections of operative intervention areas.