Open AccessTHE LEVELS OF BIOGENIC AMINES IN THE BRAIN STRUCTURE OF RATS AFTER LONG-TERM ADMINISTRATION OF DINIL, LEAD ACETATE AND TAUZINC
Author(s) -
Ivan Liakh,
В. М. Шейбак,
Е. М. Дорошенко,
O. E. Kremleva,
Darya Harshkova
Publication year - 2013
Publication title -
problemy zdorovʹâ i èkologii
Language(s) - English
Resource type - Journals
eISSN - 2708-6011
pISSN - 2220-0967
DOI - 10.51523/2708-6011.2013-10-4-20
Subject(s) - midbrain , lead acetate , serotonin , biogenic amine , hypothalamus , chemistry , endocrinology , medicine , biochemistry , toxicity , central nervous system , receptor
Objective: to correct the levels of biogenic amines in the brain of rats having received lead acetate and dinil by Tauzinc. Material and methods. The content of biogenic amines in the brain of rats having received dinil (5 mg/kg) and lead acetate (30 mg/kg) separately and together with Tauzinc was studied by HPLC. Results. Chronic administration of lead and dinil leads to changes in the concentrations of biogenic amines in the midbrain and hypothalamus. The application of Tauzinc led to normalization of the serotonin concentration in the midbrain, as well as the turnover of serotonin in midbrain and the hypothalamus.