Open AccessCOVID-19 Pneumonia After SARS-CoV-2 Vaccination with CoronaVac: A Case Series from Turkey
Author(s) -
Mehmet ÇOBAN,
Mehmet Nuri Yakar,
Murat Küçük,
Bişar Ergün,
Muammer Çelik,
Begüm Ergan,
Erdem Yaka,
Necati Gökmen
Publication year - 2022
Publication title -
turkish thoracic journal
Language(s) - English
Resource type - Journals
eISSN - 2149-2530
DOI - 10.5152/turkthoracj.2022.0201
Subject(s) - medicine , seroconversion , pneumonia , pandemic , vaccination , covid-19 , intensive care unit , disease , coronavirus , clinical trial , pediatrics , intensive care medicine , immunology , virology , infectious disease (medical specialty) , virus
Coronavirus disease 2019 is a novel viral infection that has caused a pandemic globally. Many kinds of vaccine development studies were conducted to prevent the spread and deaths. The CoronaVac is the most commonly used vaccine in Turkey. Phase 3 trials from various countries revealed that CoronaVac efficacy ranged from 50.7% to 91.25% but increased in moderate or severe cases to 100%. Additionally, it was remarkable owing to high seroconversion rates achieving up to 100%. After the vaccine campaign began in Turkey, critically ill patients continued to admit to our center's intensive care unit though they had been vaccinated with 2 doses of CoronaVac. The clinical course of these patients revealed that they are still at high risk of severe disease and death. Therefore, we aimed to share these patients' clinical characteristics and disease course, laboratory, and radiologic data.