Open AccessThe Combined Effect of Downregulated RB1 and Overexpressed lncRNA SSTRS-AS1 on Prediction Time to Castration-Resistant Prostate Cancer: Indonesian Cohort Studies
Author(s) -
Indrawarman Soerohardjo,
Andy Zulfiqqar,
Irianiwati Widodo,
Didik Setyo Heriyanto,
Sumadi Lukman Anwar
Publication year - 2022
Publication title -
türk üroloji dergisi/turkish journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.347
H-Index - 8
pISSN - 2149-3235
DOI - 10.5152/tud.2022.21282
Subject(s) - prostate cancer , medicine , oncology , cancer , prostate , gynecology
Identifying the mechanism underlying the initiation and development of castration-resistant prostate cancer remains challenging. Time to castration-resistant prostate cancer is defined by prostate-specific antigen progression and may represent a risk factor for developing immune alterations with a negative prognostic role in the overall survival of patients with prostate cancer. This study aimed to evaluate the combined effect of downregulated RB1 and overexpressed SSTR5-AS1 as biomarkers for predicting time to castrationresistant prostate cancer.