
Hemophagocytic Syndrome due to Leishmania Infection Diagnosed with Immunofluorescence Antibody Test
Author(s) -
Hakan Sarbay,
Yasemin Işık Balcı,
Selin Güler,
Meral Türk,
Mehmet Akın,
Azız Polat
Publication year - 2016
Publication title -
türkiye parazitoloji dergisi/türkiye parazitoloji dergisi
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.207
H-Index - 18
eISSN - 2146-3077
pISSN - 1300-6320
DOI - 10.5152/tpd.2016.4692
Subject(s) - leishmania infantum , visceral leishmaniasis , pancytopenia , leishmaniasis , hepatosplenomegaly , immunofluorescence , amastigote , bone marrow , leishmania , medicine , immunology , antibody , direct fluorescent antibody , serology , pathology , virology , parasite hosting , disease , world wide web , computer science
Leishmaniasis is a reticuloendothelial system disease that mostly observed before the age of 5. Visceral infection causes long-standing fever, weight loss, weakness, pancytopenia, and hepatosplenomegaly. Leishmania infantum is responsible for visceral leishmaniasis (VL) in Turkey. We present a case of hemophagocytic syndrome due to Leishmania infection diagnosed with an immunofluorescence antibody test (IFAT). Leishmania amastigotes were not observed on bone marrow aspiration. We consider that IFAT is very important for parasite detection in the diagnosis of VL in children, particularly when amastigotes are not obtained on bone marrow aspiration.