Open AccessIn Vitro and In Vivo Effects of Nonsteroidal Anti-inflammatory Drugs and Aspirin on Rabbit Esophageal Epithelium
Author(s) -
Sezgi Kıpçak,
Doga Caganoglu,
Pelin Ergün,
Serhat Bor
Publication year - 2022
Publication title -
the turkish journal of gastroenterology : the official journal of turkish society of gastroenterology
Language(s) - English
Resource type - Journals
eISSN - 2148-5607
DOI - 10.5152/tjg.2022.201168
Subject(s) - ibuprofen , aspirin , in vivo , medicine , pharmacology , epithelium , in vitro , pathology , chemistry , biology , biochemistry , microbiology and biotechnology
Gastroesophageal reflux disease has a high incidence of 23%, with 29% of those with gastroesophageal reflux disease consuming nonsteroidal anti-inflammatory drugs. There are insufficient data concerning the effects of nonsteroidal anti-inflammatory drugs on the esophageal tissue. We aimed to examine the effects of well-known nonsteroidal anti-inflammatory drugs using electrophysiologic criteria on the rabbit esophageal epithelium.