Recommendations for Hepatitis B Immunoglobulin and Antiviral Prophylaxis Against Hepatitis B Recurrence After Liver Transplantation | Zendy

Mesut Akarsu | Zendy; Soner Önem | Zendy; İlker Turan | Zendy; Gupse Adalı | Zendy; Meral Akdoğan | Zendy; Murat Akyıldız | Zendy; Murat Aladağ | Zendy; Yasemin Balaban | Zendy; Nilay Danış | Zendy; Murat Dayangaç | Zendy; Genco Gençdal | Zendy; Hale Gökcan | Zendy; Elif Sertesen | Zendy; Merve Gürakar | Zendy; Murat Harputluoğlu | Zendy; Gökhan Kabaçam | Zendy; Sedat Karademır | Zendy; Murat Kıyıcı | Zendy; Ramazan İdilman | Zendy; Zeki Karasu | Zendy

Open Access

Recommendations for Hepatitis B Immunoglobulin and Antiviral Prophylaxis Against Hepatitis B Recurrence After Liver Transplantation

Author(s) -

Mesut Akarsu,

Soner Önem,

İlker Turan,

Gupse Adalı,

Meral Akdoğan,

Murat Akyıldız,

Murat Aladağ,

Yasemin Balaban,

Nilay Danış,

Murat Dayangaç,

Genco Gençdal,

Hale Gökcan,

Elif Sertesen,

Merve Gürakar,

Murat Harputluoğlu,

Gökhan Kabaçam,

Sedat Karademır,

Murat Kıyıcı,

Ramazan İdilman,

Zeki Karasu

Publication year - 2021

Publication title -

the turkish journal of gastroenterology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.404

H-Index - 28

eISSN - 2148-5607

pISSN - 1300-4948

DOI - 10.5152/tjg.2021.21608

Subject(s) - medicine , liver transplantation , hepatitis b virus , hepatitis b , antibody , liver disease , immunology , transplantation , virology , hepatitis c virus , hepatitis , virus , gastroenterology

The combination of hepatitis B immunoglobulin and potent nucleos(t)ide analogs after liver transplantation is considered as the standard of care for prophylaxis against hepatitis B virus recurrence. However, the recommended doses, route of administration, and duration of HBIG administration remain unclear. Moreover, hepatitis B immunoglobulin-free prophylaxis with potent nucleos(t)ide analogs has shown promising disease outcomes in preventing hepatitis B virus recurrence. The current recommendations, produced by the Turkish Association for the Study of the Liver, Acute Liver Failure and Liver Transplantation Special Interest Group, suggest a reduced need for hepatitis B immunoglobulin administration with effective long-term suppression of hepatitis B virus replication using potent nucleos(t) ide analogs after liver transplantation.

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