Open AccessCorrelation Between THSD7A Expression and Tumor Characteristics of Azoxymethane-Induced Colon Cancer Model in Rats
Author(s) -
Oktay Halit Aktepe,
Taha Koray Şahin,
Gürkan Güner,
Deniz Can Güven,
Hacı Hasan Yeter,
Olcay Kurtulan,
İbrahim Hanifi Ozercan,
Ömer Dizdar,
Şuayib Yalçın
Publication year - 2021
Publication title -
pubmed central
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.404
H-Index - 28
eISSN - 2148-5607
DOI - 10.5152/tjg.2021.20899
Subject(s) - azoxymethane , medicine , immunohistochemistry , staining , pathology , thrombospondin 1 , ki 67 , cancer , colorectal cancer , thrombospondin , gastroenterology , angiogenesis , metalloproteinase , matrix metalloproteinase
Thrombospondin type 1 domain-containing 7A (THSD7A) has emerged as a new potential molecular tool for multiple tumors since that THSD7A was detected to be expressed in various malignant tumor types including colorectal cancer (CRC). Thus, we investigated the correlation between THSD7A expression and pathologic determinants of azoxymethane (AOM)-induced CRC in a rat model.