Open AccessCo-Expression of LGR5 and CD133 Cancer Stem Cell Predicts a Poor Prognosis in Patients With Gastric Cancer
Author(s) -
Wareeporn Wattanawongdon,
Theeraya Simawara Bathpho,
Taweesak Tongtawee
Publication year - 2021
Publication title -
the turkish journal of gastroenterology/the turkish journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.404
H-Index - 28
eISSN - 2148-5607
pISSN - 1300-4948
DOI - 10.5152/tjg.2021.20108
Subject(s) - lgr5 , medicine , cancer , cancer stem cell , stem cell marker , pathological , oncology , immunohistochemistry , stage (stratigraphy) , gastroenterology , lymphovascular invasion , pathology , stem cell , metastasis , biology , paleontology , genetics
The LGR5 and CD133 have been identified as cancer stem cells (CSCs) marker and prognostic marker in several cancers including gastric cancer. The purpose of the present study was to determine the association between co-expression of CSCs marker LGR5 and CD133 in patients with gastric cancer and their clinicopathological outcomes; to analyze the efficacy of co-expression of both markers in evaluating the prognosis of gastric cancer.