Open AccessFANCF hypomethylation is associated with colorectal cancer in Han Chinese
Author(s) -
Hang Yu,
Ranran Pan,
Tong Gao,
Dongping Wu,
Jieer Ying,
Shiwei Duan
Publication year - 2020
Publication title -
the turkish journal of gastroenterology/the turkish journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.404
H-Index - 28
eISSN - 2148-5607
pISSN - 1300-4948
DOI - 10.5152/tjg.2020.19394
Subject(s) - dna methylation , methylation , medicine , cancer research , fanconi anemia , colorectal cancer , cancer , microbiology and biotechnology , gene , gene expression , biology , genetics , dna repair
Fanconi anemia complement group F (FANCF) is known to be involved in DNA repair, and the overexpression of FANCF protein leads to cell proliferation and ultimately to cancer. The purpose of this study was to assess whether FANCF methylation was associated with colorectal cancer (CRC).