Open AccessIn vitro chemosensitivity in ovarian carcinoma: Comparison of three leading assays
Author(s) -
Burak Tatar,
Gökhan Boyraz,
İlker Selçuk,
Alper K. Dogan,
Alp Usubütün,
Zafer Selçuk Tuncer
Publication year - 2016
Publication title -
journal of the turkish-german gynecological association
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.346
H-Index - 16
eISSN - 1309-0399
pISSN - 1309-0380
DOI - 10.5152/jtgga.2016.16017
Subject(s) - chemosensitivity assay , ovarian carcinoma , mtt assay , ovarian cancer , carboplatin , doxorubicin , paclitaxel , cancer research , docetaxel , gemcitabine , chemotherapy , topotecan , in vitro , medicine , oncology , pathology , biology , cisplatin , cancer , biochemistry
An alternative approach to the current therapy of ovarian carcinoma is the individualization of treatment by determining the sensitivity of tumoral tissue to chemotherapeutic agents before the initiation of chemotherapy. The objectives of the study are to determine the efficacy of in vitro chemosensitivity assays in ovarian carcinoma and to measure the correlation of three leading assays.