Open AccessThe Analysis of GJB2, GJB3, and GJB6 Gene Mutations in Patients with Hereditary Non-Syndromic Hearing Loss Living in Sivas
Author(s) -
Küçük Kurtulgan H,
EE Altuntaş,
Yıldırım Me,
Öztürk Özdemir,
Binnur Bağcı,
İlhan Sezgin
Publication year - 2019
Publication title -
the journal of international advanced otology/the journal of international advanced otology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.518
H-Index - 13
eISSN - 2148-3817
pISSN - 1308-7649
DOI - 10.5152/iao.2019.5401
Subject(s) - medicine , hearing loss , compound heterozygosity , genetics , mutation , allele , genotyping , genetic analysis , audiology , gene , genotype , biology
The aim of the present study was to investigate the presence of GJB2, GJB3, and GJB6 gene mutations in non-syndromic sensorineural hearing loss (NSHL) cases living in Sivas region, to provide appropriate genetic counseling for cases who were found to have mutation, and to contribute to decrease the frequency of mutant allele in the next generation and plan treatment and rehabilitation with early diagnosis.