Open AccessPrevalence of pre-clinical autoimmunity in the normal adult population residing in a metropolitan city of India: A cross-sectional study
Author(s) -
Uma Kumar,
Maumita Kanjilal,
Lakshmy Ramakrishnan,
Maheswari Thangavelu
Publication year - 2021
Publication title -
european journal of rheumatology :/european journal of rheumatology
Language(s) - English
Resource type - Journals
eISSN - 2147-9720
pISSN - 2148-4279
DOI - 10.5152/eurjrheum.2020.20039
Subject(s) - autoantibody , medicine , anti nuclear antibody , cross sectional study , population , cohort , epidemiology , incidence (geometry) , immunology , demography , rheumatoid factor , environmental health , antibody , pathology , physics , sociology , optics
A steep rise in the incidence of autoimmune diseases over the decades has been observed, which is simply not explainable with population-level genetic changes, indicating thereby that environmental factors play an important role in their causation. Then again, how air pollution affects the immune system is still not completely elucidated. This study intends to check the presence of autoantibodies and inflammatory markers in normal adults residing for more than 10 years in a highly polluted region.