Open AccessParaoxonase Activity and Phenotype Distribution in Patients with Chronic Obstructive Pulmonary Disease
Author(s) -
Nurhan Sarıoğlu,
Çiğdem Bilen,
Celalettin Çevik,
Nahit Gençer
Publication year - 2020
Publication title -
the eurasian journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.337
H-Index - 13
eISSN - 1308-8742
pISSN - 1308-8734
DOI - 10.5152/eurasianjmed.2019.19122
Subject(s) - copd , paraoxonase , arylesterase , pon1 , phenotype , medicine , pathogenesis , case control study , gastroenterology , oxidative stress , immunology , biology , gene , genotype , genetics
Paraoxonase 1 (PON1) and arylesterase (ARE) enzymes have an important role in the prevention of oxidative stress which is related to the pathogenesis of chronic obstructive pulmonary disease (COPD). PON1 levels vary widely among individuals and ethnic groups, which is in part associated with polymorphisms.