Open AccessEvaluation of Pathologic Complete Response (pCR) to Neoadjuvant Chemotherapy in Iranian Breast Cancer Patients with Estrogen Receptor Positive and HER2 Negative and impact of predicting variables on pCR
Author(s) -
Ramesh Omranipour,
Roghiyeh Jalili,
Adel Yazdankhahkenary,
Abdolali Assarian,
Mehrzad Mirzania,
Bita Eslami
Publication year - 2020
Publication title -
meme sağlığı dergisi/meme sağlığı dergisi
Language(s) - English
Resource type - Journals
eISSN - 1306-0953
pISSN - 1306-0945
DOI - 10.5152/ejbh.2020.5487
Subject(s) - medicine , breast cancer , oncology , estrogen receptor , lymph node , receiver operating characteristic , neoadjuvant therapy , chemotherapy , progesterone receptor , axillary lymph nodes , cancer
The pathologic complete response (pCR) in the breast and axillary lymph node after neoadjuvant chemotherapy (NAC) would improve outcomes and it is used as a surrogate marker for survival. Our objective was to evaluate the breast and nodal pCR in breast cancer patients with estrogen receptor-positive (ER) and HER2 negative subtypes. Meanwhile, we sought to examine the impact of predicting factors on the rate of pCR.