Open AccessLymph Node Ratio (LNR): Predicting Prognosis after Neoadjuvant Chemotherapy (NAC) in Breast Cancer Patients
Author(s) -
Atilla Soran,
Tolga Özmen,
Arsalan Salamat,
Gürsel Soybir,
R. R. Johnson
Publication year - 2019
Publication title -
meme sağlığı dergisi/meme sağlığı dergisi
Language(s) - English
Resource type - Journals
eISSN - 1306-0953
pISSN - 1306-0945
DOI - 10.5152/ejbh.2019.4848
Subject(s) - medicine , breast cancer , lymph node , oncology , mastectomy , axillary lymph node dissection , axillary lymph nodes , chemotherapy , axilla , neoadjuvant therapy , lymph , cohort , cancer , pathology , sentinel lymph node
Axillary lymph node status is an important prognostic factor in breast cancer (BC). Residual nodal disease burden after neoadjuvant chemotherapy (NAC) is one of the important prognostic factors to determine the prognosis and in the treatment of BC. Lymph node ratio (LNR) defined as the ratio of the number of positive lymph nodes to total excised axillary lymph nodes, may be a stronger determinant of prognosis than pN in axillary nodal staging, although there is very limited data evaluating its prognostic value in the setting of NAC. In this cohort of patients, we studied the utility of LNR in predicting recurrence and overall survival (OS) after NAC.